Eva C.  Guinan , MD


Director of Translational Research, Dept of Radiation Oncology
Office Phone: 617-632-4932
Appointment Line: 1-888-PEDI-ONC (733-4662)
Fax: 617-632-3770
NPI: 1215996806

Departments/Divisions

Specialties

aplastic anemia
bone marrow failure disorders
hematology/oncology
hematopoietic stem cell transplantation
myelodysplasia
regimen-related toxicity

Services/Programs

Academic Appointments

Associate Professor of Radiation Oncology, Harvard Medical School

Certifications

Pediatrics, Pediatric Hematology/Oncology

Medical School

Harvard Medical School, Boston, MA  (1980)

Internship

Children's Hospital Boston, Boston, MA  (07/80 to 06/81)

Residency

Pediatrics, Children's Hospital Boston, Boston, MA  (07/81 to 06/82)

Fellowship

Pediatric Hematology/Oncology, Children's Hospital Boston/Dana Farber Cancer Institute, Boston, MA  (07/82 to 06/84)

Awards

Boston Magazine Top Doctors 2011 , December 2011
Boston Magazine
Richardson PG, Soiffer RJ, Antin JH, Uno H, Jin Z, Kurtzberg J, Martin PL, Steinbach G, Murray KF, Vogelsang GB, Chen AR, Krishnan A, Kernan NA, Avigan DE, Spitzer TR, Shulman HM, Di Salvo DN, Revta C, Warren D, Momtaz P, Bradwin G, Wei LJ, Iacobelli M, McDonald GB, Guinan EC. Defibrotide for the treatment of severe hepatic veno-occlusive disease and multi-organ failure post stem cell transplantation: a multi-center, randomized, dose-finding trial. Biol Blood Marrow Transplant (in press)

Davies JK, Gribben JG, Brennan LL, Yuk D, Nadler LM, Guinan EC. Outcome of alloanergized haploidentical bone marrow transplantation after ex vivo costimulatory blockade: results of two phase I studies. Blood 2008; 112(6): 2232-41

Davies JK, Nadler LM, Guinan EC. Expansion of allospecific regulatory T cells after anergized mismatched bone marrow transplantation. Sci Transl Med 2009; 1(1): 1ra3.

Bone Marrow Transplantation and Complications, Growth Factor Therapy, Bone Marrow Failure Syndromes
  • Transplantation of anergic histoincompatible bone marrow (N Engl J Med 340:1704, 1999)
  • Hematopoietic growth factors trials in pediatric bone marrow failure syndromes (Br J Haematol 103:304, 1998)· Neutrophil defense in BMT patients (Transplantation 73:1522, 2002; Pediatr Infect Dis J 22: 978, 2003)
  • Metabolism and energy expenditure after BMT (Am J Clin Nutr 78:104, 2003)
  • T cell memory after BMT (Blood 106: 1749, 2005

  • Dana-Farber Cancer Institute
    Department of Pediatric Oncology
    44 Binney Street
    Boston, MA  02115
    Phone: 617-632-4932
    Fax: 617-632-3770

Other Office Location