George Q.  Daley , MD, PhD
Director of Stem Cell Transplantation
Office Phone: 617-919-2015
Appointment Line: 1-888-PEDI-ONC (733-4662)
Fax: 617-730-0222
NPI: 1639139991

Departments/Divisions

Specialties

hematology/oncology
hematopoietic stem cell transplantation

Services/Programs

Academic Appointments

Samuel E. Lux, IV Professor of Hematology, Children's Hospital Boston, Harvard Medical School

Certifications

Hematology/Oncology

College

Harvard University , Cambridge , MA  (1982)

Graduate School

Ph.D., MIT, Cambridge, MA  (1989)

Medical School

Harvard Medical School , Boston , MA  (1991)

Internship

Mass General Hospital , Boston , MA  (1991-92)

Residency

Mass General Hospital , Boston , MA  (1992-95)

Fellowships

Research Fellowship, Whitehead Institute for Biomedical Reseach  (1995-2003)
Clinical Fellowship Hematology/Oncology, Children's Hospital Boston, Dana Farber Cancer Institute, and Brigham Women's Hospital, Boston, MA
Whitehead Institute for Biomedical Research, Cambridge , MA  (1995-2003)

Awards

E. Mead Johnson Award , 2009
American Pediatric Society and Society for Pediatric Research
Directed differentiation of HSCs from pluripotent stem cells: We study hematopoietic development in mouse embryos and differentiating cultures of human and mouse pluripotent stem cells to define the molecular genetic programs that enable formation of HSCs in experimental and therapeutic models. Our long-term goal is improved transplantation therapies for genetic and malignant blood disorders.

Derivation of genetically defined pluripotent stem cells: We use nuclear transfer, parthenogenesis, and reprogramming with defined genes to model combined cell and gene therapy of human genetic disorders.

Mechanisms of oncogenesis: We have a long-standing interest in molecular mechanisms of leukemia induction by the BCR/ABL oncoprotein in human Chronic Myeloid Leukemia, the classic malignancy of hematopoietic stem cells. Recent studies in our lab have focused on the role of the Lin28A/B genes that are linked to a variety of cancer types.

  • Children's Hospital Boston
    300 Longwood Avenue
    Karp 7214
    Boston, MA  02115
    Phone: 617-919-2015
    Fax: 617-730-0222
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