It is a privilege to see the tenacity of our patients and the way children of all ages recovery quickly from interventions.

MEDICAL SERVICES

EDUCATION

Undergraduate Degree

  • University of Queensland , 1995 , Bisbane , Australia

Medical School

  • University of Queensland , 2000 , Bisbane , Australia

Internship

  • St. George Hospital , 2002 , Sydney , Australia

Residency

  • The Canberra Hospital , 2001 , Canberra , Australia

Fellowship

  • Royal Children's Hospital , 2003 , Canberra , Australia

Philosophy of Care

I have the most remarkable job in the world and I can honestly say that I know how privileged I am to be in this role. It is a privilege to care for patients before, sometimes during and certainly after their surgery. Families are often well prepared before their admission, with advances in prenatal diagnosis and imaging detail available to have a plan for surgical intervention and appropriate counselling – but someone’s baby (or child/adolescent/partner or parent) undergoing a cardiac intervention is always a big deal.

It is a privilege to work with the extraordinary multi-disciplinary team of specialized nurses, educators, cardiac surgeons, cardiologists and dedicated cardiac intensive care physicians. We share an expectation of excellence in family centered care and a dedication to advancing this rapid-paced field.

It is a privilege to see the tenacity of our patients and the way children of all ages recovery quickly from interventions. We meet the most remarkable families – advocates and participants in their child/family member’s care, and it is a privilege to share this sometimes difficult journey with them.

Many patients who come to Boston Children’s Hospital with congenital cardiac disease for operative intervention spend only a short period in CICU, and need only a glimpse of the care we offer. But for those patients and families who need more intensive care - longer, more complicated admissions for more complicated underlying disease, we have a unique multi-disciplinary team who is ready for the challenge and prepared to share the journey.

PROFESSIONAL HISTORY

I have benefited from clinical training in the United Kingdom, Australia and Boston in the USA in Pediatric Cardiology and Critical Care Medicine. During this time, I have completed 2 fellowships in Heart Failure, Transplantation and Mechanical Circulatory Support. My clinical practice and research interests are focused around the care of these patients, who often require extended CICU admissions. Boston Children’s Hospital has been internationally renowned for clinical innovation and genuine advancement of the field of Pediatric Cardiology and Cardiac Surgery and I am delighted to be a part of this team.

PUBLICATIONS

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  1. Nair AG, Sleeper LA, Smoot LB, Wigmore D, Mecklosky J, Andren K, Bastardi HJ, Blume ED, Fynn-Thompson F, Thiagarajan RR, Alexander PMA. Extracorporeal Membrane Oxygenation Support After Heart Transplantation in Children-Outcomes of a Single Center Cohort. Pediatr Crit Care Med. 2020 04; 21(4):332-339. View abstract
  2. Zimpfer D, Alexander PMA, Davies RR, Dipchand AI, Feingold B, Joong A, Lord K, Kirk R, Scales A, Shih R, Miera O. Pediatric donor management to optimize donor heart utilization. Pediatr Transplant. 2020 05; 24(3):e13679. View abstract
  3. Kirk R, Dipchand AI, Davies RR, Miera O, Chapman G, Conway J, Denfield S, Gossett JG, Johnson J, McCulloch M, Schweiger M, Zimpfer D, Ablonczy L, Adachi I, Albert D, Alexander P, Amdani S, Amodeo A, Azeka E, Ballweg J, Beasley G, Böhmer J, Butler A, Camino M, Castro J, Chen S, Chrisant M, Christen U, Danziger-Isakov L, Das B, Everitt M, Feingold B, Fenton M, Garcia-Guereta L, Godown J, Gupta D, Irving C, Joong A, Kemna M, Khulbey SK, Kindel S, Knecht K, Lal AK, Lin K, Lord K, Möller T, Nandi D, Niesse O, Peng DM, Pérez-Blanco A, Punnoose A, Reinhardt Z, Rosenthal D, Scales A, Scheel J, Shih R, Smith J, Smits J, Thul J, Weintraub R, Zangwill S, Zuckerman WA. ISHLT consensus statement on donor organ acceptability and management in pediatric heart transplantation. J Heart Lung Transplant. 2020 Apr; 39(4):331-341. View abstract
  4. O'Halloran CP, Andren KG, Mecklosky J, Larsen S, Brediger S, Vitali S, Zalieckas JM, Fynn-Thompson F, Thiagarajan RR, Alexander PMA. Mortality and Factors Associated With Hemorrhage During Pediatric Extracorporeal Membrane Oxygenation. Pediatr Crit Care Med. 2020 01; 21(1):75-81. View abstract
  5. O'Halloran CP, Thiagarajan RR, Yarlagadda VV, Barbaro RP, Nasr VG, Rycus P, Anders M, Alexander PMA. Outcomes of Infants Supported With Extracorporeal Membrane Oxygenation Using Centrifugal Versus Roller Pumps: An Analysis From the Extracorporeal Life Support Organization Registry. Pediatr Crit Care Med. 2019 12; 20(12):1177-1184. View abstract
  6. Alexander PMA, Akcan-Arikan A, Shekerdemian LS. Another Outcome Lost to the Benefits of Levosimendan? Pediatr Crit Care Med. 2019 10; 20(10):992-994. View abstract
  7. Chiel L, Welsh S, Andren K, Mecklosky J, Alexander PMA, Casey A, Fishman MP. Pediatric Hemoptysis without Bronchiectasis or Cardiac Disease: Etiology, Recurrence, and Mortality. J Pediatr. 2019 11; 214:66-70. View abstract
  8. Lorusso R, Raffa GM, Alenizy K, Sluijpers N, Makhoul M, Brodie D, McMullan M, Wang IW, Meani P, MacLaren G, Kowalewski M, Dalton H, Barbaro R, Hou X, Cavarocchi N, Chen YS, Thiagarajan R, Alexander P, Alsoufi B, Bermudez CA, Shah AS, Haft J, D'Alessandro DA, Boeken U, Whitman GJR. Structured review of post-cardiotomy extracorporeal membrane oxygenation: part 1-Adult patients. J Heart Lung Transplant. 2019 11; 38(11):1125-1143. View abstract
  9. Nasr VG, Raman L, Barbaro RP, Guner Y, Tonna J, Ramanathan K, Pappalardo F, Thiagarajan RR, Alexander PMA. Highlights from the Extracorporeal Life Support Organization Registry: 2006-2017. ASAIO J. 2019 08; 65(6):537-544. View abstract
  10. Lorusso R, Raffa GM, Kowalewski M, Alenizy K, Sluijpers N, Makhoul M, Brodie D, McMullan M, Wang IW, Meani P, MacLaren G, Dalton H, Barbaro R, Hou X, Cavarocchi N, Chen YS, Thiagarajan R, Alexander P, Alsoufi B, Bermudez CA, Shah AS, Haft J, Oreto L, D'Alessandro DA, Boeken U, Whitman G. Structured review of post-cardiotomy extracorporeal membrane oxygenation: Part 2-pediatric patients. J Heart Lung Transplant. 2019 11; 38(11):1144-1161. View abstract
  11. Moynihan KM, Alexander PMA, Schlapbach LJ, Millar J, Jacobe S, Ravindranathan H, Croston EJ, Staffa SJ, Burns JP, Gelbart B. Epidemiology of childhood death in Australian and New Zealand intensive care units. Intensive Care Med. 2019 09; 45(9):1262-1271. View abstract
  12. Lorusso R, Alexander P, Rycus P, Barbaro R. The Extracorporeal Life Support Organization Registry: update and perspectives. Ann Cardiothorac Surg. 2019 Jan; 8(1):93-98. View abstract
  13. Alexander PMA, DiOrio M, Andren K, Gauvreau K, Mistry KP, Mathieu D, Wright J, Allan CK, Nathan M, Mayer JE, Thiagarajan RR, Bergersen L. Accurate Prediction of Congenital Heart Surgical Length of Stay Incorporating a Procedure-Based Categorical Variable. Pediatr Crit Care Med. 2018 10; 19(10):949-956. View abstract
  14. Howard TS, Kalish BT, Rajagopal SK, Williams K, Zalieckas J, Thiagarajan RR, Alexander PMA. Factors Associated With Mortality in Children Who Successfully Wean From Extracorporeal Membrane Oxygenation. Pediatr Crit Care Med. 2018 09; 19(9):875-883. View abstract
  15. O'Halloran CP, Alexander PMA, Andren KG, Mecklosky J, Salvin JW, Larsen S, Zalieckas J, Fynn-Thompson F, Thiagarajan RR. RBC Exposure in Pediatric Extracorporeal Membrane Oxygenation: Epidemiology and Factors Associated With Large Blood Transfusion Volume. Pediatr Crit Care Med. 2018 08; 19(8):767-774. View abstract
  16. Moynihan KM, Jansen MA, Liaw SN, Alexander PMA, Truog RD. An Ethical Claim for Providing Medical Recommendations in Pediatric Intensive Care. Pediatr Crit Care Med. 2018 08; 19(8):e433-e437. View abstract
  17. Alexander PMA, Nugent AW, Daubeney PEF, Lee KJ, Sleeper LA, Schuster T, Turner C, Davis AM, Semsarian C, Colan SD, Robertson T, Ramsay J, Justo R, Sholler GF, King I, Weintraub RG. Long-Term Outcomes of Hypertrophic Cardiomyopathy Diagnosed During Childhood: Results From a National Population-Based Study. Circulation. 2018 07 03; 138(1):29-36. View abstract
  18. Weintraub RG, Alexander PMA. Outcomes in Pediatric Dilated Cardiomyopathy: Quo Vadis? J Am Coll Cardiol. 2017 11 28; 70(21):2674-2676. View abstract
  19. Alexander PMA, Thiagarajan RR. Does Birth at Early-Term Gestation Increase Mortality for Neonates on Extracorporeal Life Support After Cardiac Surgery? Pediatr Crit Care Med. 2017 09; 18(9):899-900. View abstract
  20. Barbaro RP, Paden ML, Guner YS, Raman L, Ryerson LM, Alexander P, Nasr VG, Bembea MM, Rycus PT, Thiagarajan RR. Pediatric Extracorporeal Life Support Organization Registry International Report 2016. ASAIO J. 2017 Jul/Aug; 63(4):456-463. View abstract
  21. Yim DL, Jones BO, Alexander PM, d'Udekem Y, Cheung MM. Effect of anti-heart failure therapy on diastolic function in children with single-ventricle circulations. Cardiol Young. 2015 Oct; 25(7):1293-9. View abstract
  22. Singh TP, Blume ED, Alexander PM, Gauvreau K. Association of hemodynamic profiles with wait-list mortality in children listed for heart transplantation with idiopathic dilated cardiomyopathy. Am J Cardiol. 2015 Jan 15; 115(2):243-8. View abstract
  23. Alexander PM, Daubeney PE, Nugent AW, Lee KJ, Turner C, Colan SD, Robertson T, Davis AM, Ramsay J, Justo R, Sholler GF, King I, Weintraub RG. Long-term outcomes of dilated cardiomyopathy diagnosed during childhood: results from a national population-based study of childhood cardiomyopathy. Circulation. 2013 Oct 29; 128(18):2039-46. View abstract
  24. Alexander PM, Eastaugh L, Royle J, Daley AJ, Shekerdemian LS, Penny DJ. Respiratory syncytial virus immunoprophylaxis in high-risk infants with heart disease. J Paediatr Child Health. 2012 May; 48(5):395-401. View abstract
  25. Pham NM, Alexander PM, Chow CW, Jones BO, d'Udekem Y, Konstantinov IE. Anterior mediastinal lymphangioma in an infant: diagnosis and surgical management. Heart Lung Circ. 2012 May; 21(5):289-91. View abstract
  26. Purevjav E, Arimura T, Augustin S, Huby AC, Takagi K, Nunoda S, Kearney DL, Taylor MD, Terasaki F, Bos JM, Ommen SR, Shibata H, Takahashi M, Itoh-Satoh M, McKenna WJ, Murphy RT, Labeit S, Yamanaka Y, Machida N, Park JE, Alexander PM, Weintraub RG, Kitaura Y, Ackerman MJ, Kimura A, Towbin JA. Molecular basis for clinical heterogeneity in inherited cardiomyopathies due to myopalladin mutations. Hum Mol Genet. 2012 May 01; 21(9):2039-53. View abstract
  27. Bohuta L, d'Udekem Y, Best D, Alexander P, Barozzi L, Butt W. Outcomes of second-run extracorporeal life support in children: a single-institution experience. Ann Thorac Surg. 2011 Sep; 92(3):993-6. View abstract
  28. Ryerson LM, Alexander PM, Butt WW, Shann FA, Penny DJ, Shekerdemian LS. Rotating inotrope therapy in a pediatric population with decompensated heart failure. Pediatr Crit Care Med. 2011 Jan; 12(1):57-60. View abstract
  29. Breeze AC, Alexander PM, Murdoch EM, Missfelder-Lobos HH, Hackett GA, Lees CC. Obstetric and neonatal outcomes in severe fetal ventriculomegaly. Prenat Diagn. 2007 Feb; 27(2):124-9. View abstract