Diffuse Pontine Glioma

What is a diffuse intrinsic pontine glioma?

Diffuse intrinsic pontine gliomas (DIPGs) are highly aggressive and difficult to treat brain tumors found at the base of the brain. They are glial tumors, meaning they arise from the brain's glial tissue — tissue made up of cells that help support and protect the brain's neurons. These tumors are found in an area of the brainstem (the lowest, stem-like part of the brain) called the pons, which controls many of the body's most vital functions such as breathing, blood pressure, and heart rate.

Approximately 300 children are diagnosed with DIPGs each year, usually between the ages of 5 and 9. Although the prognosis for DIPGs remains very poor, new research led by Dana-Farber/Boston Children's may provide the key to improved treatment options.

Care for diffuse intrinsic pontine gliomas at Dana-Farber/Boston Children's

Children and adolescents with DIPGs are treated at Dana-Farber/Boston Children's Cancer and Blood Disorders Center through our Glioma Program, one of the world’s largest pediatric glioma treatment programs. Our brain tumor specialists have extensive expertise in treating all types of gliomas, including DIPGs.

Get more in-depth information on DIPG, including answers to:

  • How is diffuse intrinsic pontine glioma diagnosed?
  • What is the best treatment for DIPG?
  • What is the latest research on DIPG?
  • What is the long-term outlook for children with DIPG?

How and why DIPG develops.

Discover what Dr. Mariella Filbin learned by profiling more than 3,300 biopsied brain cells from children with DIPG.


Illustration of DIPG