Clinical Research

Shaping the future of pediatric medicine

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For 150 years, Boston Children’s has embodied a culture of scientific investigation that has shaped pediatric medicine and changed children’s lives. This legacy continues today as we lead the world in pediatric research, empowering clinicians and scientists to challenge the status quo and seek better answers for our patients.

Our research enterprise is the world's largest and most highly-funded pediatric hospital. In FY2018, we received more funding from the National Institutes of Health than any other children’s hospital in the nation. We perform research in a vast range of specialties, revolutionizing treatments for children with common conditions, such as asthma, diabetes and obesity, to children with rare and complex disorders.

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Find a clinical research study

Boston Children's leads or participates in hundreds of clinical trials. Use this database to find out which trials are recruiting, who can enroll and more.

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Resources for the research community

A central hub of resources to support the Boston Children’s research community through guidance on planning, designing, implementing and reporting.

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Keeping clinical research safe during COVID-19

At Boston Children's our top priority remains the health and safety of our patients, families, clinical research participants and staff. Our leadership and world-class infectious disease experts have been working closely with state and city officials to implement a safe return to full operations. We've added new precautions to limit the risk of COVID-19 transmission, so you can participate in our leading-edge clinical research studies, knowing we're committed to keeping you safe. If you have questions and are currently participating in a study, contact your study team. If you are interested in joining in a study, search our Clinical Trial Finder for the latest information.

Recent Breakthroughs

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A diabetes drug with a potential side benefit: Reduced COVID-19 mortality

In 2006, the Food and Drug Administration approved the drug sitagliptin to lower blood sugar in type 2 diabetes. Now, a multicenter observational study in Italy suggests the drug also cuts mortality in diabetic patients hospitalized with COVID-19 — by as much as half.
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Global partnership leads to improved treatment for childhood diarrhea

Diarrheal diseases remain a major childhood health problem in many parts of the world.
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Boston Children’s Hospital leads national study on pediatric COVID-19 and MIS-C

Why are children largely spared from COVID-19 — and why do a few become extremely sick? To find out, Boston Children’s Hospital launched a national study in April to perform real-time surveillance at more than 35 U.S. children’s hospitals.
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Building on our extraordinary leadership in pediatric science at Boston Children’s, we translate our findings — and those of others — to fundamentally change how disease is treated and cured.

David A. Williams, MD
Senior Vice President and Chief Scientific Officer