Oettgen Laboratory | Current Research Projects

        ·      Influence of IgE on mast cell homeostasis in the intestine

        ·      The function of food-specific IgG antibodies and signaling, via FcyRIIb, on inhibition both in   
      immediate hypersensitivity reactions mediated by mast cells and basophils as well as on APC:T cell          interactions in the intestine and the emerging Th2/Treg balance

        ·      FcyRIIb signaling pathways in mast cells

        ·      Cell intrinsic differences in basophil sensitivity to allergens as a basis of the widely variable sensitivity        of patients with food allergen-specific IgE to food ingestion