Current Environment:

By Year


Yuki K, Matsunami E, Tazawa K, Wang W, DiNardo JA, Koutsogiannaki S. Pediatric perioperative stress response and anesthesia Transl Perioper Pain Med  2017; 2: 1-12

Okuno T, Koutsogiannaki S, Ohba M, Chamberlain M, Bu W, Lin FY, Eckenhoff RG, Yokomizo T, Yuki K. Intravenous anesthetic propofol binds to 5-lipoxygenase and attenuates leukotriene B4 production. FASEB J 2017 [Epub ahead of print]

Chamberlain M, Koutsogiannaki S, Schaefers MM, Babazada H, Liu R, Yuki K. The differential effects of anesthetics on bacterial behaviors. PLOS ONE 2017; 12: e0170089

Tazawa K, Koutsogiannaki S, Chamberlain M, Yuki K. The effect of different anesthetics on tumor cytotoxicity by natural killer cells. Toxicology Letters 2017; 266: 23-31

Ferradal SL*, Yuki K* (*co-first authors), Vyas R, Ha CG, Yi F, Stopp C, Wypij D, Cheng HH, Newburger J, Kaza A, Franceschini MA, Kussamn BD, Grant EP. Noninvasive assessment of cerebral blood flow and oxygen metabolism in neonates during hypothermic cardiopulmonary bypass. Scientific Reports (in press)



Koutsogiannaki S, Schaefers MM, Okuno T, Ohba M, Yokomizo T, Priebe GP, DiNardo JA, Soriano SG, Yuki K. Prolonged exposure to volatile anesthetic isoflurane worsens the outcomes of polymicrobial abdominal sepsis. Toxicological Sciences2016 doi:10.1093/toxsci/kfw261

Liu JR, Yuki K, Baek C, Han XH, Soriano SG. Dexmedetomidine-induced neuroapoptosis is dependent on its cumulative dose. Anesth Analg 2016; 123: 1008-17

Faraoni D, Zurakowski D, Brown M, Vo D, Goobie S, Yuki K, DiNardo JA. Postoperative outcomes in children with and without congenital heart disease using non-cardiac surgery: a propensity matched analysis. J Am Coll Cardiol, 2016; 67: 793-801

Lee J, Faraoni D, Lee S, Odegard KC, Randolph A, DiNardo JA, Yuki K. Incidence and risk factors for postoperative vomiting following atrial septal defect repair in children. Pediatr Anaesth 2016; 26: 644-8

Williams MR, Atkinson DB, Bezzerides VJ, Yuki K, Franklin K, Alexander ME. Pausing with the gauze: Inhibition of temporary pacemakers by RF scan during cardiac surgery. Anesth Analg 2016; 123: 1143-8

Yuki K, Eckenhoff RG. Mechanisms of the Immunological Effects of Volatile Anesthetics: A Review. Anesth Analg 2016; 123: 326-35

Greenwald E, Yuki K. A translational consideration of intracellular adhesion molecule-1 biology in the perioperative setting. Transl Perioper Pain Med 2016; 1: 17-23



Yuki K, DiNardo JA. Comparison of actual oxygen delivery kinetics to those predicted by mathematical modeling following Stage 1 palliation just prior to superior cavopulmonary anastomosis. Paediatr Anaesth 2015; 25: 174-9

Jung S, Yuki K. Differential effects of volatile anesthetics on leukocyte integrin macrophage-1 antigen J Immunotoxicol 2015; 9: 1-9

Liu JR, Han X, Soriano SG, Yuki K. Leukocyte function-associated antigen-1 deficiency impairs responses to polymicrobial sepsis World J Clin Cases 2015; 3: 793-806


Yuki K, Murakami N. Sepsis pathophysiology and anesthetic consideration. Cardiovasc Hematol Disord Drug Targets 2015; 15: 57-69

Whiting D, Yuki K, DiNardo JA. Cardiopulmonary bypass in the pediatric population. Best Pract Res Clin Anesthesiol 2015; 29: 241-56



Kollman CS, Bai X, Tsai CH, Yang H, Lind KE, Skinner SR, Zhu Z, Israel D, Cuozzo JW, Morgan BA, Yuki K, Xie C, Springer T, Shimaoka M, Evindar G. Application of encoded library technology (ELT) to a protein-protein interaction target: discovery of a potent class of integrin lymphocyte function-associated antigen-1 (LFA-1) antagonists Bioorg Med Chem 2014: 22: 2353-65

Bu W, Pereira L, Eckenhoff RG, Yuki K. Stereoselectivity of isoflurane in adhesion molecule leukocyte function-associated antigen-1 Plos One 2014; 9: e96649

Liu JR, Han X, Soriano SG, Yuki K. The role of macrophage 1 antigen in polymicrobial sepsis. Shock 2014; 42; 532-9



Yuki K, Chilson K, DiNardo JA. Improvement of PaO2 during one-lung ventilation with partial left-heart bypass in pediatric patients is caused by increased blood flow to the dependent lung. J Cardiothroac Vasc Anesth 2013; 27: 542-5

Carbo C*, Yuki K*, Demers M, Wagner DD, Shimaoka M (* equally contributed). Isoflurane inhibits neutrophil recruitment in the cutaneous Arthus reaction model. J Anesth 2013; 27: 261-8  

Yuki K, Bu W, Shimaoka M, Eckenhoff RG. Volatile anesthetics, not intravenous anesthetic propofol bind to and attenuate the activation of platelet receptor integrin aIIbb3. PLOS ONE 2013; 8: e60415

Sen M, Yuki K, Springer TA. An internal ligand-bound, metastable state of a leukocyte integrin aXb2. J Cell Biol 2013; 203: 629-642

Yuki K, Bu W, Jin X, Shimaoka M, Eckenhoff RG. Propofol shares the binding site with isoflurane and sevoflurane on leukocyte function-associated antigen-1 Anesth Analg 2013; 117: 803-11

Bertolizio G, Yuki K, Odegard K, Collard V, DiNardo JA. Cardiac arrest and neuromuscular blockade reversal agents in the transplanted heart. J Cardiothroac Vasc Anesth 2013; 27: 1374-8



Koeberle A, Shindou H, Harayama T, Yuki K, Shimizu T Polyunsaturated fatty acids are incorporated into maturating male mouse germ cells by lysophosphatidic acid acyltransferase 3. FASEB J. 2012; 26: 169-80

Yuki K, Emani S, DiNardo JA. A mathematical model of transitional circulation toward biventricular repair in hypoplastic left heart syndrome. Anesth Analg 2012; 115: 618-26

Yuki K, Bu W, Xi J, Sen M, Shimaoka M, Eckenhoff RG. Isoflurane binds and stabilizes a closed conformation of the leukocyte function-associated antigen-1. FASEB J 2012; 26: 4408-17

Collard V, Segura LG, Daaboul DG, Yuki K. Retrograde intubation during laryngeal cleft repair on cardiopulmonary bypass. J Anesth 2012; 26: 273-4

Yuki K, Sharma R, DiNardo J. Ventricular assist device therapy in children. Best Prac Res Clin Anaesthesiol 2012; 26: 247-64



Yuki K, Soriano SG, Shimaoka M. Sedative drug modulates T-cell and lymophocyte function-associated antigen-1 function. Anesth Analg 2011; 112: 830-8

Wesley MC, Yuki K, Daaboul DG, DiNardo JA. Blood utilization in neonates and infants undergoing cardiac surgery requiring cardiopulmonary bypass. World J Pediatr Congenit Heart Surg. 2011; 2: 382-392

Daaboul DG, Yuki K, Wesley MC, DiNardo JA. Anesthetic and cardiopulmonary bypass considerations for cardiac surgery in unique pediatric patient populations: sickle cell disease and cold agglutinin disease. World J Pediatr Congenit Heart Surg. 2011; 2: 364-370

Yuki K, Casta A, Uezono S. Anesthetic management of noncardiac surgery for patients with single ventricle physiology. J Anesth 2011; 25; 247-56

Yuki K, Daaboul DG. Postoperative maladaptive behavioral changes in children. Middle East J Anaesthesiol 2011; 21: 183-9

Yuki K. Cell-free ligand-binding assays for integrin LFA-1. Methods Mol Biol 2012; 757: 73-8



Yuki K, Astrof N, Bracken C, Soriano SG, Shimaoka M.  Sevoflurane binds and allosterically blocks integrin leukocyte function-associated antigen-1 Anesthesiology 2010; 113: 600-609



Yuki K, Shindou H, Hishikawa D, Shimizu T.  Characterization of mouse lysophosphatidic acid acyltransferase 3: an enzyme with dual function in the testis.  J Lipid Res. 2009; 50: 860-869

Yuki K, Sakuramoto C, Matsumoto C, Hoshino M, Niimi,Y. The effect of left heart bypass on pulmonary blood flow and arterial oxygenation during one-lung ventilation in patients undergoing descending thoracic aortic surgery. J Clin Anesth 2009; 21: 562-566

Shindou H, Hishikawa D, Harayama T, Yuki K, Shimizu T. Recent progress on acyl-CoA: lysophospholipid acyltransferase research. J Lipid Res. 2009; 50: S46-51

Yuki K, Casta. Management of difficult airway in pediatric patients with right ventricular outflow tract obstruction. J Anesth 2009; 23: 281-283



Yuki K, Astrof N, Bracken C, Yoo R, Silkworth W, Soriano SG, Shimaoka M. The volatile anesthetic isoflurane perturbs conformational activation of integrin LFA-1 by binding to the allosteric regulatory cavity.  FASEB J 2008; 22: 4109-4116

Casta A, Brown DW, Yuki K. Induction of supraventricular tachycardia during transesophageal echocardiography: an unusual complication. J Cardiothorac Vasc Anesth 2008; 22: 592-3

Yuki K, Shamberger RC, McGowan FX Jr, Seefelder C. The perioperative management of a patient with Fontan physiology for pheochromocytoma resection. J Cardiothorac Vasc Anesth 2008; 22: 748-50



Yuki K, Chilson K, Odegard KC, DiNardo JA. Trendelenburg position, simulated Valsalva maneuver, and liver compression do not alter the size of the right internal jugular vein in patients with a bidirectional Glenn shunt. Anesth Analg 2007; 105: 365-8